The United States turns one-quarter of a millennium old this year, and the St. Louis area has contributed significantly to its history.
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William Clark, co-leader of the expedition in 1804-06. After returning to St. Louis, he served for many years as federal Indian agent, both for the territory and after Missouri became a state. Married twice, he had seven children and died in St. Louis in 1838. He is buried in Bellefontaine Cemetery.Â
In photos: Dred and Harriet Scott's visible legacy in St. Louis
Scott was denied freedom by the U.S. Supreme Court, which upheld a Missouri Supreme Court decision that Scott, who had been taken to free states, was not free because Black people were not considered citizens under the U.S. Constitution.
A painting of Harriet and Dred Scott that was hung in 1973 in the Old Courthouse in St. Louis.
Susan Blow opened the nation's first successful public kindergarten, at Des Peres School in the Carondelet neighborhood, near her family's estate.Â
Irma Rombauer, born in St. Louis in 1877 (her father was famous doctor Max Starkoff), wrote "The Joy of Cooking," which became famous, especially, for its chatty style and voice.Â
Thomas Stearns Eliot, poet, born in St. Louis in 1888, back in town on Jan. 16, 1933, to speak on William Shakespeare at Washington University. It was the first visit by Eliot, 44, since he left for Europe in 1914.
Dr. Carl Ferdinand Cori and his wife, Dr. Gerty Theresa Cori, conduct experiments at their laboratory at the Washington University in St. Louis, Mo., on Oct. 30, 1947. The biochemists are awarded the Nobel Prize for Physiology or Medicine for their research in isolating the enzyme that begins the conversion process of animal starch into sugar within the body. (AP Photo)
Playwright Tennessee Williams at his typewriter in 1940Â in New York
Dr. William Masters and Virginia Johnson, director and assistant director of the Reproductive Biology Research Foundation and co-authors of "Human Sexual Response," in 1970.Â
Phyllis Schlafly, chairwoman of GOP Women's Organization, is shown in St. Louis, Jan. 17, 1973.
The logo for Twitter appears above a trading post on the floor of the New York Stock Exchange, Monday, Nov. 29, 2021.Â
Twitter co-founder Jack DorseyÂ
Sept. 28, 2010 - The Square plug-in device is demonstrated with an iPhone. It makes accepting credit card payments easy for vendors by reading swiped credit cards.

